EXBIO/抗胡CD8太平洋蓝™/100项测试/PB-817-T100
商品编号：
PB-817-T100
品牌：
EXBIO
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product details
Images
References
Isotype
Mouse IgG1
Specificity
The mouse monoclonal antibody LT8 recognizes an extracellular epitope of CD8, a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. This antibody blocks Leu2 binding.
Workshop
HLDA V, HLDA VII
Application
FC (QC tested)
Application details
Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Reactivity
Non-human primates, Human
Immunogen
human blood lymphocytes
Other names
p32, LEU2
Preparation
The purified antibody is conjugated with Pacific Blue™ under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Formulation
Stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide
Storage and handling
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Exbio licence note
The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden.Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s.
Licence note
Alexa Fluor®, Pacific Blue™ and Pacific Orange™ are registered trademarks of Life Technologies Corporation.
Licence label
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com.
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD8 (LT8) Pacific Blue™ antibody (4 μl reagent / 100 μl of peripheral whole blood).
Separation of human CD8 positive lymphocytes (red-filled) from CD8 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD8 (LT8) Pacific Blue™ antibody (4 μl reagent / 100 μl of peripheral whole blood).
General references:
Devine L, Thakral D, Nag S, Dobbins J, Hodsdon ME, Kavathas PB: Mapping the binding site on CD8 beta for MHC class I reveals mutants with enhanced binding. J Immunol. 2006 Sep 15;177(6):3930-8. PubMed
Pang DJ, Hayday AC, Bijlmakers MJ: CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers. J Biol Chem. 2007 May 4;282(18):13884-94. PubMed
van den Berg HA, Wooldridge L, Laugel B, Sewell AK: Coreceptor CD8-driven modulation of T cell antigen receptor specificity. J Theor Biol. 2007 Nov 21;249(2):395-408. PubMed
Product specific references:
Ivanidze J, Hoffmann R, Lochmüller H, Engel AG, Hohlfeld R, Dornmair K: Inclusion body myositis: laser microdissection reveals differential up-regulation of IFN-γ signaling cascade in attacked versus nonattacked myofibers. Am J Pathol. 2011 Sep;179(3):1347-59.PubMed
Agea E, Russano A, Bistoni O, Mannucci R, Nicoletti I, Corazzi L, Postle AD, De Libero G, Porcelli SA, Spinozzi F: Human CD1-restricted T cell recognition of lipids from pollens. J Exp Med. 2005 Jul 18;202(2):295-308.PubMed
Held K, Bhonsle-Deeng L, Siewert K, Sato W, Beltrán E, Schmidt S, Rühl G, Ng JK, Engerer P, Moser M, Klinkert WE, Babbe H, Misgeld T, Wekerle H, Laplaud DA, Hohlfeld R, Dornmair K: αβ T-cell receptors from multiple sclerosis brain lesions show MAIT cell-related features. Neurol Neuroimmunol Neuroinflamm. 2015 May 7;2(4):e107.PubMed
Nelson M, Loveday M: Exploring the innate immunological response of an alternative nonhuman primate model of infectious disease; the common marmoset. J Immunol Res. 2014;2014:913632.PubMed
品牌介绍
EXBIO的优质抗体（GMP）目录 ＃产品名称克隆Reg。状态应用数量价钱ED7660SingleFlowEx CD71 APC新MEM-75RUO（GMP）足球俱乐部1毫升440.00美元ED7114SingleFlowEx CD25太平洋蓝™新MEM-181RUO（GMP）足球俱乐部1毫升440.00美元ED7252SingleFlowEx CD235a FITC新JC159RUO（GMP）足球俱乐部1毫升360.00美元ED7116SingleFlowEx CD25 PE新MEM-181RUO（GMP）足球俱乐部1毫升440.00美元ED7605SingleFlowEx CD138太平洋蓝™新MI15RUO（GMP）足球俱乐部1毫升440.00美元ED7165SingleFlowEx CD71 APC-Cy™7新MEM-75RUO（GMP）足球俱乐部1毫升500.00美元ED7228SingleFlowEx CD1a APC新SK9RUO（GMP）足球俱乐部1毫升440.00美元ED7115SingleFlowEx CD25 FITC新MEM-181RUO（GMP）足球俱乐部1毫升360.00美元ED7247SingleFlowEx CD305 PE新NKTA255RUO（GMP）足球俱乐部1毫升440.00美元ED7615SingleFlowEx CD235a PE-Cy™7新JC159RUO（GMP）足球俱乐部1毫升500.00美元ED7117SingleFlowEx CD25 APC新MEM-181RUO（GMP）足球俱乐部1毫升440.00美元ED7215SingleFlowEx CD103 APC新Ber-ACT8RUO（GMP）足球俱乐部1毫升440.00美元ED7219SingleFlowEx CD138 FITC新MI15RUO（GMP）足球俱乐部1毫升360.00美元ED7224SingleFlowEx CD138 PerCP-Cy™5.5新MI15RUO（GMP）足球俱乐部1毫升600.00美元ED7164SingleFlowEx CD71 Alexa Fluor系列700新MEM-75RUO（GMP）足球俱乐部1毫升440.00美元ED7253SingleFlowEx CD235a PE新JC159RUO（GMP）足球俱乐部1毫升440.00美元
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